Logos: Medical Research Agency, National Recovery and Resilience Plan, European Union — European Recovery Fund

Project co-financed by the Medical Research Agency under the National Recovery and Resilience Plan (KPO), component D, investment D3.1.1. Competition number: 2024/ABM/03/KPO.

Research project · EPIMOD-CLL

Innovative diagnostic-prognostic panel for chronic lymphocytic leukemia

Project funded by the Medical Research Agency under KPO. Conducted by the Department of Clinical Biochemistry, CM UMK in Bydgoszcz.

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17,2 mln PLN Project value
14,9 mln PLN EU funding
> 6 mln PLN Purchase of equipment
2024–2026 Implementation period

About the project

Innovative diagnostic and prognostic panel for early diagnosis of chronic lymphocytic leukemia

The aim of the project is to develop a practical diagnostic and prognostic panel based on quantitative assessment of nucleic acid modifications in cells and biological material from CLL patients. The procedures developed are intended to increase the sensitivity and specificity of diagnostics, facilitate early differential diagnosis (e.g., CLL vs. MBL/SLL), improve prognosis assessment, and enable more effective monitoring of response to therapy, including minimal residual disease (MRD).

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Research areas

Three pillars of an innovative diagnostic and prognostic panel

Molecular diagnostics of CLL

Identification and validation of molecular biomarkers of chronic lymphocytic leukemia using NGS sequencing and flow cytometry methods.

AI predictive models

Development of machine learning algorithms integrating clinical, genomic, and proteomic data for predicting the course of CLL.

Diagnostic panel

Development of an innovative diagnostic and prognostic panel ready for implementation in clinical hematology practice.

News

Latest information on project implementation

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